Explain the importance of cytokines and their receptors in immune system development and responses.

Explain the importance of cytokines and their receptors in immune system development and responses.

Summarize the biology of B lymphocytes, from origin to surface molecules.

Summarize the biology of T lymphocytes, from origin to surface molecules.

Analyze the reactions of T and B lymphocytes with each other as well as with other cell types.

Explain the importance of cytokines and their receptors in immune system development and responses.

Format your paper consistent with APA guidelines. Use at least 3 to 5 different references in your paper.

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Transplantation Issue: Volume 86(3), 15 August 2008, pp 384-390 Copyright: (C) 2008 Lippincott Williams & Wilkins, Inc. Publication Type: [Editorials and Perspectives: Overview] DOI: 10.1097/TP.0b013e31817c90f5 ISSN: 0041-1337 Accession: 00007890-200808150-00003 Keywords: Renal transplantation, HLA antibody detection, Sensitized patients [Editorials and Perspectives: Overview] Tools for Human Leukocyte Antigen Antibody Detection and Their Application to Transplanting Sensitized Patients Fuggle, Susan V.1,2,3,5; Martin, Susan4 Author Information 1 Transplant Immunology and Immunogenetics, Oxford Transplant Centre, Churchill Hospital, Oxford, United Kingdom. 2 Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom. 3 UK Transplant, Bristol, United Kingdom. 4 Transplantation Laboratory, Manchester Royal Infirmary, Manchester, United Kingdom. 5 Address correspondence to: Susan V. Fuggle, Ph.D., Transplant Immunology and Immunogenetics, Oxford Transplant Centre, Churchill Hospital, Oxford OX3 7LJ, United Kingdom. E-mail: susan.fuggle@nds.ox.ac.uk Received 8 January 2008. Revision requested 11 February 2008. Accepted 14 April 2008. ———————————————- Outline Abstract Antibody Identification Complement Dependent Cytotoxicity Flow Cytometry Solid Phase Assays Enzyme-Linked Immunosorbent Assay Flow Cytometry Luminex Patient Sensitization Profile Transplanting Sensitized Patients ACKNOWLEDGMENTS REFERENCES Abstract In recent years there have been major advances in the technology for the detection and definition of human leukocyte antigen antibodies. In this overview we describe the evolution in laboratory technology, the techniques currently available and consider their application in antibody specificity definition and in understanding a…

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