Which of the findings from the nursing assessment demonstrate possible adverse effects from the drug therapy?(5 pts)

Which of the findings from the nursing assessment demonstrate possible adverse effects from the drug therapy?(5 pts)

ANTITUBERCULARS

Wanda McKay is 36 years old and homeless, although she sleeps in a shelter nightly and has been going
to a day programfor the past5 weeks, where she showers, receives hermail, gets some counseling, and has
hermeals. She is being treated daily for tuberculosis with directly observed therapy (DOT) and has been
receiving this treatment for the last 6 months. She had a tubal ligation 5 years ago with no
complications and is not currently sexually active. She was last tested for HIV and hepatitis C 2
months ago and was negative. She has been vaccinated for hepatitis B. She drinks, but does notuse
drugs, and hasnot been prescribed any psychiatric medications. When she was admitted into the day
treatment program, her hospital records were sentindicating that she is sputumculture negative, so she
is not a risk to others in closequarters.
When hernurse comes to the day programto administer her meds today, she notices that the sclera of her
eyeshave a yellow tintto them. She is broughtinto the mobile center and examined by the nurse
practitioner.Data obtained fromthe nursing assessment includethe following:
•The patient complains of abdominal pain, nausea.
•The patient is tender to palpation of liver.
•Lung soundsclear
•Chest x-ray clear
•Vital signs: temperature, 100.2°F; pulse, 88;respirations, 20; blood pressure, 130/80
The patient’s current medications include:isoniazid, 300 mg q day;rifampin, 600mg q day; and
ethambutol, 800mg q day.
Case StudyQuestions
1. Provide therationale for whyMs. McKay is prescribedthis combination ofdrugs. (5 pts)
2. Whatcontraindications or precautions would eliminate the use ofthese drugsfor Ms.
McKay?(5 pts)
3. What patient variables are most important to consider forMs. McKay when assessing her drug
therapy?(10 pts)
4. Whataspects of core drug knowledge(pharmacotherapeutics, pharmacokinetics, and
pharmacodynamics)are especially relevantto consider because they may interact with the patient
variables?(5 pts)
5. Which of the findings fromthe nursing assessmentdemonstrate the effectiveness of drug therapy?(5
pts)